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Progress In Research Spring 2025

Marco Baptista, Ph.D., Chief Scientific OfficerFor far too long, individuals living with spinal cord injuries (SCI) have waited for a breakthrough — something designed specifically for their needs, something that doesn’t just manage symptoms but actively improves their lives. Now, for the first time in history, we have it.

The ARCEX® System is the first-ever FDA-approved technology developed specifically for the SCI community, marking a monumental step forward in our mission to deliver real, life-changing solutions. The Christopher & Dana Reeve Foundation played a critical role in bringing this technology forward, ensuring that innovation in SCI research leads to tangible outcomes — not just theories or distant possibilities, but real, functional gains. 

This is a historic moment — and we celebrate it — but our work is far from over. Instead, this milestone underscores the importance of our work and proves what we’ve always believed: meaningful progress is possible, and it only happens with bold investment and active collaborations.

The approval of ARCEX® is just the beginning. Now, we must push even harder to pursue other groundbreaking therapies, ensuring that the SCI community has access to the full spectrum of solutions they deserve.  

To advance these efforts, the Christopher & Dana Reeve Foundation will announce new grants awarded via our recently launched Requests for Application (RFAs) from industry and academia seeking support for preclinical research. We are eager to invest in a diverse range of approaches — from repurposed drugs to gene therapy approaches, and more — ensuring we explore every promising avenue to drive progress toward meaningful recovery. 

This is a time of unprecedented momentum. With your support, we can accelerate the development of new technologies, therapeutics and interventions that will further transform lives. Together, we can ensure ARCEX® is the first of many victories for the SCI community. 

Marco Baptista, Ph.D., Chief Scientific Officer

Download the full newsletter here (PDF).

Also Included

FDA Approves ARC-EX® System

Reeve Foundation partner, ONWARD Medical, announces world’s first FDA-approved non-invasive spinal cord stimulation system for people with chronic spinal cord injury.

Advancing the Next Generation of Breakthroughs

To bridge critical gaps, the Reeve Foundation and Spinal Research (UK) are partnering on a novel approach to advancing SCI research with a joint call for RFAs.

SCI Investors Symposium 2025

Expanding Collaboration, Accelerating ProgressSCI Investors Symposium logo

The third annual SCI Investors Symposium, co-presented by the Reeve Foundation and Lineage Cell Therapeutics, Inc., is set for June 27, 2025 (to be held virtually), will once again unite key organizations to drive innovation in SCI research.

“As in previous years, the 2025 SCI Investors Symposium will include presentations featuring both preclinical and clinical research, offering deeper insights into what’s moving through the pipeline toward human trials,” says Marco Baptista, Ph.D., Chief Scientific Officer of the Christopher & Dana Reeve Foundation. “At the heart of these conversations is a commitment to patient-driven, needs-based research, ensuring that therapeutic development aligns with the priorities of people living with SCI.”

As the SCI field continues to evolve, collaboration is essential. The SCI Investors Symposium is more than a conference — it’s a working event where the brightest minds in science, industry, and advocacy come together to break down silos, tackle shared challenges, and accelerate progress toward new treatment paradigms.

By bringing together researchers, industry leaders, and individuals with lived experience, the event fosters meaningful dialogue about what truly matters to the SCI community. These discussions play a critical role in shaping research strategies and guiding the development of therapies that will have real-world impact.

Upcoming Event: Reeve Golf Classic

Tee Up for SCI DiscoveryReeve Golf Classic

This year’s Reeve Golf Classic will tee off on August 18, 2025, at the legendary Winged Foot Golf Club in Mamaroneck, NY!

This exclusive event offers the rare opportunity to play one of the nation’s most prestigious courses — all while advancing our mission: to cure SCI and improve the lives of those living with paralysis. Last year’s event raised over $800,000 for groundbreaking research and life-changing programs.

Enjoy a full day of world-class golf, gourmet dining, and lively entertainment, all in support of innovation and hope. Whether you’re competing on the course or joining as a sponsor, your participation makes an impact.

Golfers, please register by Thursday, May 15.

For sponsorship opportunities, contact [email protected]. Let’s make every swing count!

 

Spotlights

Scientific Advisory Board Spotlight: Armin Curt, M.D.

In Zurich, Curt set out to understand spinal cord physiology, and how that physiology changes in response to different types of injuries.

Team Reeve Spotlight: Martin Quinn

On April 21, Martin will compete in the Boston Marathon to raise funds for the Christopher & Dana Reeve Foundation.

Super/Man: The Christopher Reeve Story

Super/Man: The Christopher Reeve StoryTwenty years after Christopher Reeve’s passing, Super/Man: The Christopher Reeve Story brings SCI to the global spotlight — a level of visibility too often denied to those living with disabilities — while offering a deeper look at the ambitions and complexities that defined Reeve’s life.

Though the world knew him as Superman, those closest to him remember a man who was so much more. He was an athlete, an advocate, a husband, a father — and a tireless champion for SCI research. The film doesn’t shy away from the full scope of his life, balancing his remarkable achievements with the unflinching realities of his personal struggles, including his relentless pursuit of medical breakthroughs.

“We wanted whoever made this to create a 360-degree portrait of a human who was incredible and flawed, who was heroic and brave, who had fears and worries,” says Matthew Reeve, a member of the Reeve Foundation Board of Directors.

Yet, Super/Man isn’t just a retrospective — it’s a call to action. As the film garnered critical and commercial acclaim, it also sparked meaningful conversations about disability and the ongoing fight for progress. For the Reeve family and the Foundation, that dialogue is a testament to Christopher’s enduring impact.

“The Reeve Foundation is a central element of my parents’ legacy,” Will Reeve, also a Board member, says. “My siblings and I were intent on showing the good work that the Foundation did during my parents’ lifetimes, has done since their deaths, and will continue to do as far into the future as it needs to exist.”

From personal tragedy to national advocacy, Christopher and Dana Reeve’s mission continues. In recognition of their legacy and the vital work that lies ahead, Warner Bros. Discovery has made a generous donation to support the Reeve Foundation — helping to carry forward the vision of a world in which spinal cord injury does not result in paralysis and paralysis does not result in diminished quality of life.

Join Us!

For more than 20 years, the Reeve Foundation has operated the National Paralysis Resource Center (NPRC) through a competitive cooperative grant housed at the U.S. Department of Health and Human Services (HHS).  

The Reeve Foundation is the only federally funded entity dedicated to directly supporting the paralysis community. As the recognized leader in the field, we provide free, comprehensive information and personalized resources directly to the paralysis community. Through our Quality of Life Grants program, we have invested more than $46 million in nonprofit organizations that empower people living with paralysis, their families and caregivers across all 50 states, Washington D.C., and U.S. territories. 

This work is made possible through the congressional appropriations process, for which we actively advocate each year. Your voice is powerful in ensuring the NPRC remains a lifeline for those who need it most. Join our advocacy efforts today.

Additionally, your donations strengthen our ability to create a future where spinal cord injury doesn’t result in paralysis, and paralysis does not result in diminished quality of life. Please consider making a gift to sustain this mission.

Together, we can ensure this work continues.  Thank you.

Donate today to advance SCI and paralysis research.